PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID

The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4...

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Main Authors RISS, BERNHARD, CISZEWSKI, LECH, BÄNZIGER, MARKUS, WAYKOLE, LILADHAR, MURLIDHAR, NAPP, MATTHIAS, HAWKER, STEVEN, HOOK, DAVID, WIETFELD, BERNHARD, RUCH, THOMAS, SEDELMEIER, GOTTFRIED
Format Patent
LanguageEnglish
French
German
Published 10.08.2016
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Summary:The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
Bibliography:Application Number: EP20080706986