DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF BISOPROLOL

The present invention relates to a percutaneous administration device of bisoprolol, which includes a backing; and a pressure-sensitive adhesive layer containing bisoprolol, which is laminated on one surface of the backing, wherein the maximum value of a release rate of bisoprolol during a period of...

Full description

Saved in:
Bibliographic Details
Main Authors YUASA, SHUICHIRO, MATSUOKA, KENSUKE, IWAO, YOSHIHIRO, MINAMI, KUNIHIRO, OKADA, KATSUHIRO
Format Patent
LanguageEnglish
French
German
Published 03.07.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to a percutaneous administration device of bisoprolol, which includes a backing; and a pressure-sensitive adhesive layer containing bisoprolol, which is laminated on one surface of the backing, wherein the maximum value of a release rate of bisoprolol during a period of from immediately after the application on skin until a lapse of 24 hours is 30 µg/cm 2 /hr or less; and wherein the release rate of bisoprolol at the time of a lapse of 24 hours after the application on skin is 10 µg/cm 2 /hr or less. The percutaneous administration device of the present invention is reduced in the skin irritation during the application, especially at the time of peeling, and is capable of persistently administrating a therapeutically or preventively effective amount of bisoprolol into a living body.
Bibliography:Application Number: EP20080721442