Stabilized solid pharmaceutical composition of candesartan cilexetil

The present invention relates to a solid pharmaceutical composition containing candesartan cilexetil as active ingredient and a stabilizing agent selected from the group consisting of esters of saturated fatty acids and monohydroxy alcohols, esters of hydroxycarboxylic acids and monohydroxy alcohols...

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Main Authors CONDE AGUILAR, SUSANA, DEL CURA MEDINA, ESTIBALIZ, JURADO SANCHEZ, FRANCISCO, MORENO RUEDA, JUAN, ARROYO HIDALGO, SERGIO, JOHANSSON, MONA
Format Patent
LanguageEnglish
French
German
Published 05.06.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a solid pharmaceutical composition containing candesartan cilexetil as active ingredient and a stabilizing agent selected from the group consisting of esters of saturated fatty acids and monohydroxy alcohols, esters of hydroxycarboxylic acids and monohydroxy alcohols, ethers of C1-C4 monohydroxy alcohols and C2-C9 polyhydroxy alcohols, saturated fatty acid alkaline salts, panthenol, and/or mixtures thereof. The invention also relates to a process for its preparation and its use for formulation of oral solid dosage forms of candesartan cilexetil. The active substance in the compositions comprising the stabilizing agent exhibits good stability over time.
Bibliography:Application Number: EP20070847376