PEPTIDE CHIMERIC MOLECULES HAVING ANTIVIRAL PROPERTIES AGAINST VIRUSES OF THE FLAVIVIRIDAE FAMILY

The present invention is relative to chimerical peptides, whose primary structure holds at least one segment which inhibits the activation of the NS3 protease of a virus from the Flaviviridae family, they also contain a cell penetrating segment and they are capable of inhibiting or attenuate the vir...

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Main Authors CHINEA SANTIAGO, GLAY, GUIROLA CRUZ, OSMANY, TOLEDO MAYORA, PATRICIA, GABRIELA, FLEITAS SALAZAR, NORALVIS, GARAY PEREZ, HILDA ELISA, CABRALES RICO, ANIA, HUERTA GALINDO, VIVIAN, MUSACCHIO LASA, ALEXIS, SARRIA NUNEZ, MONICA, REYES ACOSTA, OSVALDO, MARTIN DUNN, ALEJANDRO MIGUEL
Format Patent
LanguageEnglish
French
German
Published 25.07.2012
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention is relative to chimerical peptides, whose primary structure holds at least one segment which inhibits the activation of the NS3 protease of a virus from the Flaviviridae family, they also contain a cell penetrating segment and they are capable of inhibiting or attenuate the viral infection. This invention is also relative to pharmaceutical compounds which contain these chimerical peptides for the prevention and/or treatment of the infection caused by a virus of the Flaviviridae family.
Bibliography:Application Number: EP20070817384