CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF

The present invention features compounds of formula (I) or pharmaceutically acceptable salts or solvates thereof, for use in inhibiting the metabolizing activities of CYP enzymes and for use in improving the pharmacokinetics of drugs that are metabolized by CYP enzymes.

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Bibliographic Details
Main Authors HUTCHINSON, DOUGLAS, K, CHEN, HUI-JU, FLENTGE, CHARLES, A, HUANG, PEGGY, P, KEMPF, DALE, J, YEUNG, MING, C, RANDOLPH, JOHN, T, KLEIN, LARRY, L
Format Patent
LanguageEnglish
French
German
Published 29.07.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention features compounds of formula (I) or pharmaceutically acceptable salts or solvates thereof, for use in inhibiting the metabolizing activities of CYP enzymes and for use in improving the pharmacokinetics of drugs that are metabolized by CYP enzymes.
Bibliography:Application Number: EP20070814515