PYRIDO (2, 3-D) PYRIMIDIN0NE COMPOUNDS AND THEIR USE AS PI3 INHIBITORS

The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).

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Bibliographic Details
Main Authors KANIA, ROBERT, STEVEN, NAMBU, MITCHELL, DAVID, TRAN, KHANH, TUAN, PLEWE, MICHAEL, BRUNO, LE, PHUONG, THI, QUY, BHUMRALKAR, DILIP, PAIRISH, MASON, ALAN, JOHNSON, MARY, CATHERINE, CHENG, HENGMIAO, HOFFMAN, JACQUI, ELIZABET, DRESS, KLAUS, RUPRECHT
Format Patent
LanguageEnglish
French
German
Published 01.07.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).
Bibliography:Application Number: EP20070804890