PROGASTRIN INHIBITORS IN THE TREATMENT OF COLON CANCER

The present invention relates to inhibitors of progastrin induced repression of ICAT for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells and cells in which the beta-catenin/Tcf-4-mediated transcriptional pathway is constitutivel...

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Main Authors BOURGAUX, Jean-François, JOUBERT, Dominique, JAY, Philippe, PANNEQUIN, Julie, DELAUNAY, Nathalie, HOLLANDE, Frédéric
Format Patent
LanguageEnglish
French
German
Published 27.02.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to inhibitors of progastrin induced repression of ICAT for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells and cells in which the beta-catenin/Tcf-4-mediated transcriptional pathway is constitutively active.
Bibliography:Application Number: EP20070734620