SITE-SPECIFIC INHIBITORS OF HISTONE METHYLTRANSFERASE [HMTASE] AND PROCESS OF PREPARATION THEREOF
The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is -OCH3 or -OH, R2 and R2 is -OH or -OAc; a process of isolating compound of structural formula Ia, where R1 and R1 is -OCH3, R2 and R2 is -OH; a process of p...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
25.03.2009
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is -OCH3 or -OH, R2 and R2 is -OH or -OAc; a process of isolating compound of structural formula Ia, where R1 and R1 is -OCH3, R2 and R2 is -OH; a process of preparation of compound of structural formula Ib, where R1 and R1 is -OCH3, R2 and R2 is -OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is -OH, R2 and R2 is -OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof. |
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Bibliography: | Application Number: EP20070805629 |