MEDICAMENT RESERVOIRS FOR MEDICAL IMPLANTS

• Main Authors: KLOCKE, BJÖRN, HARDER, CLAUS, DIENER, TOBIAS, FRINGES, MATTHIAS
• Format: Patent
• Language: English; French; German
• Published: 23.03.2016
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

Production of an active substance depot (1), which is formed for the mechanical connection with a surface of an endovascular implantable body, comprises (a) providing one or more polymers, (b) providing one or more active substances and (c) producing an active substance depot from the polymers and the active substances, where the active substance depot is formed in such a way that it is mechanically connectable by force effect and/or adhesive application with the surface of the body. Independent claims are included for: (1) production of an active substance-loaded endovascular implantable body, comprising (d) providing an endovascular implantable body, (e) providing one or more different active substance depots and (f) mechanically connecting the active substance depot with the body; (2) the active substance-loaded endovascular implantable body, produced by the above process; (3) a kit comprising one or more active substance depots and one or more endovascular implantable bodies; and (4) preventing or treating stenosis, aneurism or tumor tissues in a human or an animal body, comprising providing an endovascular implantable body, providing one or more different active substance depots, mechanically connecting the active substance depot with the body and implanting the active substance-loaded body into a blood vessel, where the blood is introduced to the tumor tissue. ACTIVITY : Vasotropic; Cytostatic. MECHANISM OF ACTION : None given.