HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condit...

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Main Authors AYALA, LETICIA, HEGDE, SAYEE,G, KOIS, ADAM, SLOSS, MARIANNE, K, NADOLNY, LISA, HUGHES, KEVIN, ALBERS, RONALD, J, PLANTEVIN-KRENITSKY, VERONIQUE, SAHASRAMUDHE, KIRAN, MCCARRICK, MEG, SATOH, YOSHITAKA, SAPIENZA, JOHN, SUDBECK, ELISE, PALANKI,MOORTHY, S.S, HILGRAF, ROBERT, DELGADO MEDEROS, MARIA, MERCEDES, WRIGHT, JONATHAN, CLAREEN, STEVEN, S
Format Patent
LanguageEnglish
French
German
Published 07.01.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
Bibliography:Application Number: EP20070756113