METHOD OF EVALUATING CELL FUNCTION, SYSTEM FOR EVALUATING CELL FUNCTION, FLUORESCENT MICROSCOPE SYSTEM, PHOTOTHERAPY METHOD AND PHOTOTHERAPY SYSTEM
A proposition of the present invention is to accurately evaluate a phototoxic property (cell function) concerning a living cell. To this end, an evaluating method of cell function of the present invention includes the operations of dyeing a specific site (41) of the living cell (40) with a fluoresce...
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Main Authors | , |
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Format | Patent |
Language | English French German |
Published |
17.12.2008
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Subjects | |
Online Access | Get full text |
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Summary: | A proposition of the present invention is to accurately evaluate a phototoxic property (cell function) concerning a living cell. To this end, an evaluating method of cell function of the present invention includes the operations of dyeing a specific site (41) of the living cell (40) with a fluorescent dye, irradiating the living cell (40) with light to measure changes in brightness of resulting fluorescence generated at an adjacent site (43) of the specific site (41), and evaluating the phototoxic property based on the brightness changes. In the event of functional depression in the specific site (41), the fluorescent dye cannot be retained therein and is extravasated into the adjacent site (43) through the membrane of the specific site. The present invention can measure the extent of this extravasation, making it possible to accurately evaluate the phototoxic property. |
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Bibliography: | Application Number: EP20070736970 |