MODIFIED MACROMOLECULE
The present invention relates to a macromolecule having a controlled terminal group stoichiometry, the macromolecule including a surface layer, at least one subsurface layer and at least two terminal groups including: a first terminal group which is a residue of a pharmaceutically active agent, a de...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | English French German |
Published |
02.11.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a macromolecule having a controlled terminal group stoichiometry, the macromolecule including a surface layer, at least one subsurface layer and at least two terminal groups including: a first terminal group which is a residue of a pharmaceutically active agent, a derivative thereof or precursor therefor; and a second terminal group selected to modify the pharmacokinetics of the pharmaceutically active agent and/or macromolecule, wherein terminal group stoichiometry refers to the number and type of terminal groups. |
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Bibliography: | Application Number: EP20060721507 |