SELF-EMULSIFYING FORMULATIONS OF CETP INHIBITORS

A liquid formulation for oral administration of the CETP inhibitor of formula (I) has improved bioavailability compared with conventional solid formulations. The formulation comprises the CETP inhibitor, or a pharmaceutically acceptable salt thereof; an oil; and one or more nonionic surfactants havi...

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Bibliographic Details
Main Authors ALANI, LAMAN, L, SHETH, AGAM R, CRUANES, MARIA, T, GHOSH, SOUMOJEET, MCKELVEY, CRAIG, A, REGE, BHAGWANT
Format Patent
LanguageEnglish
French
German
Published 13.07.2011
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A liquid formulation for oral administration of the CETP inhibitor of formula (I) has improved bioavailability compared with conventional solid formulations. The formulation comprises the CETP inhibitor, or a pharmaceutically acceptable salt thereof; an oil; and one or more nonionic surfactants having a hydrophilic lipophilic balance (HLB)>10.
Bibliography:Application Number: EP20060839075