BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases.

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Bibliographic Details
Main Authors HOOD, JOHN, MC PHERSON, ANDREW, SOLL, RICHARD, M, LOHSE, DAN, MAK, CHI, CHING, NORONHA, GLENN, RENICK, JOEL, CAO, JON, JIANGUO, PATHAK, VED, ZENG, BINQI
Format Patent
LanguageEnglish
French
German
Published 12.01.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases.
Bibliography:Application Number: EP20060836583