Novel cyclohexenone compounds from antrodia camphorata and application thereof

• Main Authors: KUO, MAO-TIEN, FOK, K-HENG, WEN, WU, HUANG, CHUN-HUNG, TSOU, WAN-LING, LIU, SHENG-YUN, LI, YA-YING, CHANG, CHUNGOU
• Format: Patent
• Language: English; French; German
• Published: 11.05.2011
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorata , in particular to 4-hydroxy-2,3-dimethoxy-6-methy-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, and its use in tumor growth inhibition. The compound of the invention, which has never been discovered in Antrodia camphorata , can be applied in inhibiting the growth of cancer cells, such as breast cancer, hepatic cancer and prostate cancer; and be used as a pharmaceutical composition to inhibit the tumor growth; or further be applied in prevention of heart and blood vessel disease or dietary supplements for health needs through its antioxidant activity.