ALPHA, ALPHA`-DIHYDROXY KETONE DERIVATIVES AND USE THEREOF AS UV FILTER

Dihydroxyketone derivatives (A) are new. Dihydroxyketone derivatives (A) of formulae (I) and (II) are new. R-CH(OH)-CO-Sp-A (I) A *>-Sp *>-C(R)(OH)-CO-CH(OH)-Sp-A (II) R : hydrogen or -(CHOH) n-CH 2OH; n : 0-2; Sp and Sp *>CHOH, (CH 2) n, (CH=CH) n, (CH=CH-CH 2) n, (CH 2) n-X-(CH 2) o, (CH...

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Bibliographic Details
Main Authors BUCHHOLZ, HERWIG, RUDOLPH, THOMAS
Format Patent
LanguageEnglish
French
German
Published 27.01.2010
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Dihydroxyketone derivatives (A) are new. Dihydroxyketone derivatives (A) of formulae (I) and (II) are new. R-CH(OH)-CO-Sp-A (I) A *>-Sp *>-C(R)(OH)-CO-CH(OH)-Sp-A (II) R : hydrogen or -(CHOH) n-CH 2OH; n : 0-2; Sp and Sp *>CHOH, (CH 2) n, (CH=CH) n, (CH=CH-CH 2) n, (CH 2) n-X-(CH 2) o, (CH 2X) n-(CH 2) o, (CH 2) n-CX-(CH 2) o-X-(CH 2) p, (CH 2) nX-(CH 2) o-CX-(CH 2) p or (CH 2) n-CX-(CH 2) o; n, p and o each : 0-20; X : O, N or S; each A and A *> = substituent that absorbs UV light or a conjugated system of at least 4 pi electrons. Independent claims are included for the following: (1) oxo-dioxolan derivatives of formula (III); and (2) method for preparing (I) and (II). R 1 and R 2each hydrogen, alkyl, phenyl or aryl. [Image] ACTIVITY : Dermatological. No details of tests for dermatological activity are given. MECHANISM OF ACTION : Absorption of UV-light.
Bibliography:Application Number: EP20060805782