A COMPOSITION COMPRISING AN EXTRACT OF TIARELL POLYPHYLLA AND TIARELLIC ACID ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY
The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Tiarella polyphylla and the tiarellic acid isolated therefrom shows the inhibitory ef...
Saved in:
Main Authors | , , , , , , , , , , , , , , , , , , , |
---|---|
Format | Patent |
Language | English French German |
Published |
20.10.2010
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Tiarella polyphylla and the tiarellic acid isolated therefrom shows the inhibitory effect on the LTC4 release in vitro test and the suppressive effect on the IgE level and the cytokine(IL-4, IL-5 and IL- 13) production, airway hyperresponsiveness, and leukocyte infiltration in OVA-induced asthmatic mice. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease. |
---|---|
AbstractList | The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Tiarella polyphylla and the tiarellic acid isolated therefrom shows the inhibitory effect on the LTC4 release in vitro test and the suppressive effect on the IgE level and the cytokine(IL-4, IL-5 and IL- 13) production, airway hyperresponsiveness, and leukocyte infiltration in OVA-induced asthmatic mice. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease. |
Author | HAN, GYOON HEE KIM, SO YOUNG AHN, KYUNG SEOP KIM, DOO YOUNG LEE, HYEONG KYU KWON, OK KYOUNG PARK, BO YOUNG QUAN, GUI HUA KIM, JOO HEON KIM, GUN CHEOL OH, SEI RYANG LEE, JOONG KU SHEN, GUANG HAI KIM, JUNG HEE PARK, HEA YOUNG KIM, MI JIN CHOI, SOON JA LEE, SAN KU MIN, BYUNG SUN KIM, EUN AH |
Author_xml | – fullname: SHEN, GUANG HAI – fullname: KIM, GUN CHEOL – fullname: HAN, GYOON HEE – fullname: MIN, BYUNG SUN – fullname: QUAN, GUI HUA – fullname: KIM, DOO YOUNG – fullname: OH, SEI RYANG – fullname: PARK, HEA YOUNG – fullname: KWON, OK KYOUNG – fullname: PARK, BO YOUNG – fullname: KIM, MI JIN – fullname: LEE, HYEONG KYU – fullname: LEE, SAN KU – fullname: AHN, KYUNG SEOP – fullname: KIM, JOO HEON – fullname: KIM, SO YOUNG – fullname: CHOI, SOON JA – fullname: LEE, JOONG KU – fullname: KIM, JUNG HEE – fullname: KIM, EUN AH |
BookMark | eNqNjD0OwjAMRjvAwN8dfAAY-BsYrTQllpymSq2KTqhCYUJtJTgQR6UE2JlsPb3vTZNR27VhkjwRlLOFK0nI5fH3VFJ-BMxBn8SjEnAZCKHXzFA4rgtTM-MgpD9MClBRClQ6RtEDN9rrzDsLBqtPTYjyjNFaFOfrZSTIrP3xvR5aEZRiBiH2hCqSep6Mr83tHhbfO0sg06LMKvTdOdz75hLa8DjrYn3Y7Nb7A-62fygv4KdGug |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | ZUSAMMENSETZUNG ENTHALTEND EINEN EXTRAKT VON TIARELLA POLYPHYLLA UND DAVON ISOLIERTE TIARELLASÄURE MIT ENTZÜNDUNGSHEMMENDER, ANTIALLERGISCHER UND ANTIASTHMATISCHER WIRKUNG COMPOSITION COMPRENANT UN EXTRAIT DE TIARELLA POLYPHYLLA ET ACIDE TIARELLIQUE ISOLE A PARTIR DE CELUI-CI PRESENTANT UNE ACTIVITE ANTI-INFLAMMATOIRE, ANTIALLERGIQUE ET ANTIASTHMATIQUE |
ExternalDocumentID | EP1924159A4 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_EP1924159A43 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 15:10:06 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French German |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_EP1924159A43 |
Notes | Application Number: EP20060783327 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20101020&DB=EPODOC&CC=EP&NR=1924159A4 |
ParticipantIDs | epo_espacenet_EP1924159A4 |
PublicationCentury | 2000 |
PublicationDate | 20101020 |
PublicationDateYYYYMMDD | 2010-10-20 |
PublicationDate_xml | – month: 10 year: 2010 text: 20101020 day: 20 |
PublicationDecade | 2010 |
PublicationYear | 2010 |
RelatedCompanies | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
RelatedCompanies_xml | – name: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
Score | 2.7830284 |
Snippet | The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory,... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
Title | A COMPOSITION COMPRISING AN EXTRACT OF TIARELL POLYPHYLLA AND TIARELLIC ACID ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20101020&DB=EPODOC&locale=&CC=EP&NR=1924159A4 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT8IwFG4QjXpT1Ii_0oPhJBEom3AgpnQdq-nWZVQCJ8JgJFyACMZ_xz_V1wroRZMdXl67L2mX19f3XvsNoftJRhqwGzIZ9wkEKCR1yilxxuWRmz41Uzd1ydSyfUZu8Fp_6Tv9HJpt78JYntAPS44IFjUGe1_b9Xr5k8Ty7NnK1WM6A9Xi2dctr7SJjquGIa1S8totHitPsRJjIJWipGXiDPDctL6H9s0u2tDs817bXEpZ_vYo_gk6iAFsvj5FuWxeQEds--O1AjoMN_VuEDemtzpDnxQzFcaqK0xSycqJ6Iqog2mEeV8nlGmsfKwFTbiUOFZyEAcDKSl08LZqwTBlwsOiqySFRQvrgCfcT1SIA9r7RtNCRL6kYUi1SgYPVkOl5EnHvA1YVtHVAXSweFr0hB6cI-xzzYIyDHW4m9Yhj3eTQi5Qfr6YZ5cIO6NJVnOmpJo1G4bMHdy5S9xR3cnqzoiQcREV_4S5-qftGh3bwjs8tcoNyq_f3rNb8Ofr9M5-iS_SHJi- |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT8IwFG4QjXhT1Ig_ezCcJAJlAw7ElG5j1W5dRiVwIgxGwgWIYPx3_FN9rYBeNNnh5bX7knZ5fX3vtd8Qup-kpAG7IZ1xn0CAQhKrlBBrXBrZSb2Z2IlNpobtM7T919pz3-pn0Gx7F8bwhH4YckSwqDHY-9qs18ufJJZjzlauHpMZqBZPnmo5xU10XNEMaeWi0265kXQkKzIGUjGMWzrOAM9Na3tov67JefXOqdfWl1KWvz2Kd4wOIgCbr09QJp3nUY5tf7yWR4fBpt4N4sb0Vqfok2Img0h2uU4qGTnmXR52MA2x21cxZQpLDytOY1cIHEkxiPyBEBQ6OFs1Z5gy7mDelYLCooWV78auF8sA-7T3jaY4Dz1Bg4AqGQ8ejIYK4cYd_TZgGUVX-dDB4Cne42pwhrDnKuaXYKjD3bQO3Wg3KeQcZeeLeXqBsDWapFVrSipps6HJ3MGd28Qe1ay0Zo0IGRdQ4U-Yy3_a7lDOV4EYCh6-XKEjU4SHp1q-Rtn123t6A759ndyar_IFIaebqw |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=A+COMPOSITION+COMPRISING+AN+EXTRACT+OF+TIARELL+POLYPHYLLA+AND+TIARELLIC+ACID+ISOLATED+THEREFROM+HAVING+ANTIINFLAMMATORY%2C+ANTIALLERGIC+AND+ANTIASTHMATIC+ACTIVITY&rft.inventor=SHEN%2C+GUANG+HAI&rft.inventor=KIM%2C+GUN+CHEOL&rft.inventor=HAN%2C+GYOON+HEE&rft.inventor=MIN%2C+BYUNG+SUN&rft.inventor=QUAN%2C+GUI+HUA&rft.inventor=KIM%2C+DOO+YOUNG&rft.inventor=OH%2C+SEI+RYANG&rft.inventor=PARK%2C+HEA+YOUNG&rft.inventor=KWON%2C+OK+KYOUNG&rft.inventor=PARK%2C+BO+YOUNG&rft.inventor=KIM%2C+MI+JIN&rft.inventor=LEE%2C+HYEONG+KYU&rft.inventor=LEE%2C+SAN+KU&rft.inventor=AHN%2C+KYUNG+SEOP&rft.inventor=KIM%2C+JOO+HEON&rft.inventor=KIM%2C+SO+YOUNG&rft.inventor=CHOI%2C+SOON+JA&rft.inventor=LEE%2C+JOONG+KU&rft.inventor=KIM%2C+JUNG+HEE&rft.inventor=KIM%2C+EUN+AH&rft.date=2010-10-20&rft.externalDBID=A4&rft.externalDocID=EP1924159A4 |