THIENOTRIAZOLODIAZEPINE COMPOUND AND A MEDICINAL USE THEREOF

[Solving means] A thienotriazolodiazepine compound of the following formula (I) a pharmaceutical agent containing the compound as an active ingredient, and a production intermediate and a production method of the thienotriazolodiazepine compound. [Effect] Since this compound has an inhibitory action...

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Main Authors OSHITA, KOUICHI, SUGAHARA, KUNIO, HAMADA, MAIKO, TANAKA, MINORU, ISHIBUCHI, SEIGO, FUJIE, NAOTO, MURATA, MEGURU, ADACHI, KUNITOMO, HIKAWA, HIDEMASA, ENDOH, JUN-ICHI
Format Patent
LanguageEnglish
French
German
Published 08.06.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:[Solving means] A thienotriazolodiazepine compound of the following formula (I) a pharmaceutical agent containing the compound as an active ingredient, and a production intermediate and a production method of the thienotriazolodiazepine compound. [Effect] Since this compound has an inhibitory action on costimulatory signal from CD28 on T cell, it is useful for the prophylaxis or suppression of rejection reaction in transplantation of organ or bone marrow and the like, and the prophylaxis or treatment of autoimmune diseases or allergic diseases.
Bibliography:Application Number: EP20060756705