HALOGENATED QUINDOLINE DIMERS FOR THE TREATMENT OF CANCER

The invention provides quindoline dimers where at least one quindoline moiety is substituted in the 2-position of the quindoline scaffold by an halogen atom. The compounds of the invention show advantageous properties as cytotoxic agents for their use as medicaments against cancer.

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Bibliographic Details
Main Authors AYMAMI BOFARULL, JUAN, NAVARRO MUNOZ, ISABEL
Format Patent
LanguageEnglish
French
German
Published 06.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides quindoline dimers where at least one quindoline moiety is substituted in the 2-position of the quindoline scaffold by an halogen atom. The compounds of the invention show advantageous properties as cytotoxic agents for their use as medicaments against cancer.
Bibliography:Application Number: EP20060763131