PHARMACEUTICAL FORMS WITH IMPROVED PHARMACOKINETIC PROPERTIES

Formulation (I) that disintegrates quickly in the mouth, comprises vardenafil, where at least 80% of the vardenafil dose dissolves at 25[deg]C in 10 ml of physiological saline and the release rate of (I) in 900 ml of physiological saline is at least 70% within the first 5 minutes in the USP (titaniu...

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Bibliographic Details
Main Authors HEINIG, ROLAND, PAULI, KERSTIN, SERNO, PETER, HAYAUCHI, YUTAKA
Format Patent
LanguageEnglish
French
German
Published 11.04.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Formulation (I) that disintegrates quickly in the mouth, comprises vardenafil, where at least 80% of the vardenafil dose dissolves at 25[deg]C in 10 ml of physiological saline and the release rate of (I) in 900 ml of physiological saline is at least 70% within the first 5 minutes in the USP (titanium dioxide) sheet agitator device at 50 revolutions per minute at 37[deg]C. ACTIVITY : None given. MECHANISM OF ACTION : Cyclic guanosine monophosphate phosphodiesterase inhibitor. No biological data given.
Bibliography:Application Number: EP20060706994