REAGENT FOR ASSAYING ANTIGEN AND METHOD OF ASSAYING ANTIGEN

It is intended to provide a reagent and an assay method whereby an antigen can be conveniently and accurately assayed without resorting to any special antibody. Using two or more carriers having different particle sizes, a carrier having a smaller particle size is sensitized with at least one monocl...

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Bibliographic Details
Main Authors MIYAZAKI, O, MATSUO, M, SAITO, KAZUNORI, HONJO, YUKI, KOTANI, KAZUO, AKIMOTO, YUKA, YAGO, HIROKAZU
Format Patent
LanguageEnglish
French
German
Published 11.06.2008
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:It is intended to provide a reagent and an assay method whereby an antigen can be conveniently and accurately assayed without resorting to any special antibody. Using two or more carriers having different particle sizes, a carrier having a smaller particle size is sensitized with at least one monoclonal antibody, which is selected from among three monoclonal antibodies being reactive with both of a free antigen and a complex antigen and having different recognition sites from each other, while a carrier having a larger particle size is sensitized with the remainder monoclonal antibodies, thereby providing an assay reagent and an assay method whereby the reactivities of a free antigen and a complex antigen can be controlled.
Bibliography:Application Number: EP20050819685