Sequential drug delivery systems

The invention relates to methods and composition for improving absorption and dissolution of active ingredients of drugs. The invention provides a method of administration of an active ingredient to a mammal through a transmucosal route that includes delivering the active ingredient to a desired sit...

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Bibliographic Details
Main Authors HONTZ, JOHN, SIEBERT, JOHN M, PATHER, S. INDIRAN
Format Patent
LanguageEnglish
French
German
Published 15.08.2007
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to methods and composition for improving absorption and dissolution of active ingredients of drugs. The invention provides a method of administration of an active ingredient to a mammal through a transmucosal route that includes delivering the active ingredient to a desired site in a body of the mammal, and, sequentially, at the desired site, promoting dissolution and absorption of the active ingredient. In a preferred embodiment, the ph of the localized environment of the active ingredient is sequentially modified to promote dissolution and absorption.
Bibliography:Application Number: EP20070006505