Stable oxaliplatin formulation

A storage stable pharmaceutical composition comprising a solution of Oxaliplatin in water and a catalytic amount of a carbohydrate. A process for forming such pharmaceutical composition comprising dissolving a known amount of Oxaliplatin in water; adding an amount of carbohydrate in the range of 0.0...

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Bibliographic Details
Main Authors SINGH, AJEET KUMAR, JAIN, DEEPTI, MUKHARJEE, RAMA, PANANCHUKUNNATH, MANOJ KUMAR, BURMAN, ANAND C, PARSHOTAMDAS, DEEPAK JUDGELAL, UPADHYAY, SATISH CHANDRA
Format Patent
LanguageEnglish
French
German
Published 23.07.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A storage stable pharmaceutical composition comprising a solution of Oxaliplatin in water and a catalytic amount of a carbohydrate. A process for forming such pharmaceutical composition comprising dissolving a known amount of Oxaliplatin in water; adding an amount of carbohydrate in the range of 0.0010 % to 0.05% w/v with respect to such solution; agitating the mixture to get clear solution; filtering it through a filter membrane under aseptic conditions; and filling the solution resulting into glass vials sealed with elastomeric stoppers and aluminium flip-off seals.
Bibliography:Application Number: EP20060254598