COMBINATION COMPRISING A BCRP INHIBITOR AND 4-(4-METHYLPIPERAZIN-1-YLMETHYL)-N-Ý4-METHYL-3-(4-PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)PHENYL¨-BENZAMIDE

The present invention relates to a combination which comprises a BCRP inhibitor and Compound I of formula (I), in which the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier fo...

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Bibliographic Details
Main Authors CIPRIANI, GRETA, BREEDVELD, PAULINE, VAN TELLINGEN, OLAF, SCHELLENS, JOHANNES, HENRICUS, MATTHIAS, WIELINGA, PIETER, ROELAND, PLUIM, DICK
Format Patent
LanguageEnglish
French
German
Published 04.04.2007
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a combination which comprises a BCRP inhibitor and Compound I of formula (I), in which the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, especially in the delay of progression or treatment of cancer, and to pharmaceutical compositions comprising such combinations.
Bibliography:Application Number: EP20050758801