GAS1 UNIVERSAL LEADER

Disclosed is a method of producing an immunoglobulin heavy chain variable domain polypeptide comprising: culturing a host cell which has been transformed with a polynucleotide molecule encoding said immunoglobulin heavy chain variable domain polypeptide under conditions to express said immunoglobuli...

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Bibliographic Details
Main Author DE WILDT, RUDOLPH, M., T
Format Patent
LanguageEnglish
French
German
Published 01.09.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:Disclosed is a method of producing an immunoglobulin heavy chain variable domain polypeptide comprising: culturing a host cell which has been transformed with a polynucleotide molecule encoding said immunoglobulin heavy chain variable domain polypeptide under conditions to express said immunoglobulin heavy chain variable domain polypeptide wherein said polynucleotide molecule comprises a nucleic acid encoding a GAS1 secretion signal peptide operably linked to the immunoglobulin heavy chain variable domain polypeptide.
Bibliography:Application Number: EP20050729650