BOB-1 SPECIFIC T CELLS AND METHODS TO USE
The present invention refers to the use of Bob-1 protein, fragments or epitopes thereof and/or related sequences in a method to identify, to induce and/or to isolate Bob-1 specific or Bob-1 cross-reactive T-cells, preferably cytotoxic T-lymphocytes (CTL) and CD4<+> T-helper cells. The T-cells...
Saved in:
Main Authors | , |
---|---|
Format | Patent |
Language | English French German |
Published |
03.01.2007
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The present invention refers to the use of Bob-1 protein, fragments or epitopes thereof and/or related sequences in a method to identify, to induce and/or to isolate Bob-1 specific or Bob-1 cross-reactive T-cells, preferably cytotoxic T-lymphocytes (CTL) and CD4<+> T-helper cells. The T-cells according to the invention can be used to identify and diagnose various diseases, which are influenced by Bob-1 protein expression. The invention provides further the use of Bob-1 specific and/or Bob-1 cross-reactive T-cells, as well as peptides and/or nucleic acid sequences for inducing Bob-1 specific and/or Bob-1 cross-reactive T-cells, as medicament or vaccine and for the treatment of Bob-1 expressing tumors, lymphomas and autoimmune diseases. |
---|---|
Bibliography: | Application Number: EP20050729963 |