NOVEL RECOMBINANT ANIMAL CELLS WITH HIGH PROTEIN PRODUCTION, METHOD OF CONSTRUCTING THE SAME AND METHOD OF MASS PROTEIN PRODUCTION USING THE SAME
A gene encoding a production amount-potentiating factor is introduced into an animal cell to transform the cell. Alternatively, a protein production gene and the gene encoding the production amount-potentiating factor are introduced into the animal cell to transform the cell. Herein, as the producti...
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Main Authors | , , , , |
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Format | Patent |
Language | English French German |
Published |
21.04.2010
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Subjects | |
Online Access | Get full text |
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Summary: | A gene encoding a production amount-potentiating factor is introduced into an animal cell to transform the cell. Alternatively, a protein production gene and the gene encoding the production amount-potentiating factor are introduced into the animal cell to transform the cell. Herein, as the production amount potentiating factor, there is used a factor having caspase activity inhibiting activity and/or protein biosynthesis activity potentiating action, for example, baculovirus P35. Further, the animal cell is cultured by a culturing method under a condition that apoptosis is not induced, so that a protein is mass-produced. |
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Bibliography: | Application Number: EP20040817298 |