AMPLIFICATION OF SIGNAL USING A BEAD-BASED OLIGONUCLEOTIDE ASSAY

The present invention regards amplification of a signal from a hybridization-based oligonucleotide assay. In some embodiments, a bead comprises an oligonucleotide hybridized to a labeled polynucleotide from a sample, and a signal generated from a complex thereof is amplified through labeled antibodi...

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Main Authors TORONTALI, SUZANNE, MARIE, JUHLIN, KENTON, DUANE, TIESMAN, JAY, PATRICK, JUMP, MARY, LYNN, NACIFF, JORGE, MANUEL, RICHARDSON, BRIAN, DAVID
Format Patent
LanguageEnglish
French
German
Published 05.07.2006
Edition7
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Summary:The present invention regards amplification of a signal from a hybridization-based oligonucleotide assay. In some embodiments, a bead comprises an oligonucleotide hybridized to a labeled polynucleotide from a sample, and a signal generated from a complex thereof is amplified through labeled antibodies directed to a receptor for the label. In particular embodiments, the assay provides information on gene expression.
Bibliography:Application Number: EP20040817359