AMPLIFICATION OF SIGNAL USING A BEAD-BASED OLIGONUCLEOTIDE ASSAY
The present invention regards amplification of a signal from a hybridization-based oligonucleotide assay. In some embodiments, a bead comprises an oligonucleotide hybridized to a labeled polynucleotide from a sample, and a signal generated from a complex thereof is amplified through labeled antibodi...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French German |
Published |
05.07.2006
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | The present invention regards amplification of a signal from a hybridization-based oligonucleotide assay. In some embodiments, a bead comprises an oligonucleotide hybridized to a labeled polynucleotide from a sample, and a signal generated from a complex thereof is amplified through labeled antibodies directed to a receptor for the label. In particular embodiments, the assay provides information on gene expression. |
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Bibliography: | Application Number: EP20040817359 |