BIOACTIVE PEPTIDE-PRODUCING STRAINS OF i ENTEROCOCCUS FAECALIS /i , BIOACTIVE PEPTIDES AND APPLICATIONS THEREOF

• Main Authors: QUIROS DEL BOSQUE, ANA, RECIO SANCHEZ, ISIDRA, ALEIXANDRE DE ARTINANO, MA, AMAYA, RAMOS GONZALEZ, MERCEDES, MUGUERZA MARQUINEZ, BEGONA, DELGADO DELGADO, MARCO ANTONIO
• Format: Patent
• Language: English; French; German
• Published: 29.03.2006
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The invention relates to Enterococcus faecalis bacteria which can produce bioactive peptides, such as peptides with angiotensin converting enzyme inhibitor activity and/or antihypertensive activity. The aforementioned bacteria can be used to ferment a substrate comprising one or more proteins, peptides or fragments thereof which contain the amino acid sequence of said bioactive peptides. Moreover, the above-mentioned bacteria and bioactive peptides can be used in the pharmaceutical and food industries for the preparation of pharmaceutical compositions or functional food products.