Computer-aided techniques for analyzing biological sequences

Computer-aided techniques for analyzing biological sequences like nucleic acids are provided. The computer system may analyze hybridization intensities indicating hybridization affinity between nucleic acid probes and a sample nucleic acid sequence in order to call bases in the sample sequence. Mult...

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Main Authors MORRIS, MACDONALD S, MITTMAN, MICHAEL P, LOCKHART, DAVID J, BERNHART, DEREK, WEBSTER, TERESA A, HO, MING-HSIU, JEVONS, LUIS C
Format Patent
LanguageEnglish
French
German
Published 08.03.2006
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Summary:Computer-aided techniques for analyzing biological sequences like nucleic acids are provided. The computer system may analyze hybridization intensities indicating hybridization affinity between nucleic acid probes and a sample nucleic acid sequence in order to call bases in the sample sequence. Multiple base calls may be combined to form a single base call. Additionally, the computer system may analyze hybridization intensities in order to monitor gene expression or the change in gene expression as compared to a baseline.
Bibliography:Application Number: EP20050004961