SUBSTITUTED ANILIDE LIGANDS FOR THE THYROID RECEPTOR

Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or...

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Main Authors RAHIMI- GHADIM, MAHMOUD, WASHBURN, WILLIAM, N, MENG, WEI, RYONO, DENIS, E, MALM, JOHAN, ELLSWORTH, BRUCE, A, GARG, NEERAJ, ERICSSON, THOMAS
Format Patent
LanguageEnglish
French
German
Published 21.03.2007
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount.
Bibliography:Application Number: EP20040704944