Methods and materials relating to neuronal guidance molecule-like (NGM-like) polypeptides and polynucleotides

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted NGM-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from at least cDNA libraries prepared from adult...

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Main Authors GODBOLE, SHUBHADA, D, PALENCIA, SEREANDO, DRMANAC, RADOJE, T, BOYLE, BRYAN, J, TANG, Y., TOM, LUI, CHENGHUA, ARTERBURN, MATTHEW, C, YEUNG, GEORGE, KUO, CHIAOYUN
Format Patent
LanguageEnglish
French
German
Published 14.09.2005
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMES
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted NGM-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from at least cDNA libraries prepared from adult spleen mRNA (GIBCO) (Hyseq clone identification numbers 3073928 (SEQ ID NO: 1), and from infant brain mRNA (Columbia University) (Hyseq clone identification number 6346549) (SEQ ID NO: 18). Other aspects of the invention include vectors containing processes for producing novel human secreted NGM-like polypeptides, and antibodies specific for such polypeptides.
Bibliography:Application Number: EP20050005504