PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA

The invention relates to novel chemical compounds, pharmaceutically acceptable derivatives thereof, processes for their preparation, pharmaceutical compositions containing them, and to their use in medicine, particularly use in the amelioration of a clinical condition for which a thrombin inhibitor...

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Main Authors SMITH, STEPHEN ALLAN, SHAH, GITA PUNJABHAI, YOUNG, ROBERT JOHN, BORTHWICK, ALAN DAVID, WATSON, NIGEL STEPHEN, WEST, ROBERT IAN, SENGER, STEFAN, CHAN, CHUEN, KELLY, HENRY ANDERSON, SMITH, STEVEN, PEACE, SIMON
Format Patent
LanguageEnglish
French
German
Published 23.07.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to novel chemical compounds, pharmaceutically acceptable derivatives thereof, processes for their preparation, pharmaceutical compositions containing them, and to their use in medicine, particularly use in the amelioration of a clinical condition for which a thrombin inhibitor is indicated.
Bibliography:Application Number: EP20030780129