PROCESS FOR THE PREPARATION OF QUATERNARY N-ALKYL MORPHINAN ALKALOID SALTS

A process for the preparation of a quaternary derivative of the morphinan alkaloid, the process comprising contacting a tertiary N-substituted morphinan alkaloid with an alkyl halide in an anhydrous solvent system, wherein the solvent system comprises an aprotic dipolar solvent with the aprotic dipo...

Full description

Saved in:
Bibliographic Details
Main Authors HALVACHS, ROBERT, E, CANTRELL, GARY, L
Format Patent
LanguageEnglish
French
German
Published 30.09.2009
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:A process for the preparation of a quaternary derivative of the morphinan alkaloid, the process comprising contacting a tertiary N-substituted morphinan alkaloid with an alkyl halide in an anhydrous solvent system, wherein the solvent system comprises an aprotic dipolar solvent with the aprotic dipolar solvent constituting at least 25 wt % of the solvent system.
Bibliography:Application Number: EP20030783211