DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS

A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obe...

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Main Authors STUCKY, RUSSELL, DEAN, CHAPPELL, MARK, DONALD, SIEGEL, MILES, GOODMAN, SMITH, DANA, RAE, WOLFE, CHAD, NOLAN, FRITZ, JAMES, ERWIN, PEDREGAL-TERCERO, CONCEPCION, DIAZ BUEZO, NURIA, TAKEUCHI, KUMIKO, HOLLOWAY, WILLIAM, GLEN, QUIMBY, STEVEN, JAMES, BLANCO-PILLADO, MARIA-JESUS, DE LA TORRE, MARTA, GARCIA, THOMAS, ELIZABETH, MARIE, MATT, JAMES, EDWARD, JUNIOR, MITCH, CHARLES, HOWARD
Format Patent
LanguageEnglish
French
German
Published 21.05.2008
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.
Bibliography:Application Number: EP20030751877