BETA-2-GLYCOPROTEIN 1 IS AN INHIBITOR OF ANGIOGENESIS

The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked 2-Glycoprotein 1 ( GP1) to cells associated with the tissue. The presence of 2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization int...

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Bibliographic Details
Main Authors MCCARTY, MARYA, F, SCHROIT, ALAN, JAY, BALASUBRAMANIAN, KRISHNAKUMAR
Format Patent
LanguageEnglish
French
German
Published 20.06.2007
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked 2-Glycoprotein 1 ( GP1) to cells associated with the tissue. The presence of 2GP1 inhibits angiogenesis within the tissue, in part by preventing neovascularization into the tissue. The disclosure also provides a method for treating tumors by providing 2GP1 to the tumor.
Bibliography:Application Number: EP20030755330