SCHIZOPHRENIA ASSOCIATED GENES

• Main Authors: PICKARD, BENJAMIN, SIMON, MORS, OLE, EWALD, HENRIK, LYKKE, BLACKWOOD, DOUGLAS, MUIR, WALTER JOHN, PORTEOUS, DAVID JOHN
• Format: Patent
• Language: English; French; German
• Published: 05.01.2005
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW BREEDS OF ANIMALS; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; TRAPPING; VINEGAR; WINE

The present invention relates to the identification of genes which have been disrupted in patients diagnosed as suffering from schizophrenia and/or bi-polar affective disorder, as well as proteins encoded by the gene and antibodies thereto and to uses of such products as medicaments for treating schizophrenia and/or affective psychosis. The invention also relates to methods for diagnosing, patients suffering or predisposed to schizophrenia and/or affective psychosis, as well as screens for developing novel treatment regimes for schizophrenia and/or affective psychosis.