AMELIORANT FOR CHEMICAL TREATMENT OF CANCER

An ameliorating agent for cancer chemotherapy is disclosed, which comprises a chromanol glucoside represented by the following general formula (1) (wherein R , R , R , and R , which are identical or different from each other, stand for a hydrogen atom or a lower alkyl group, R stands for a hydrogen...

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Main Authors VASILIEVA, LUBOV SERGEEVNA, VOLKOVA, LUDMILA MIHAILOVNA, KAGIYA, TSUTOMU, MURASE, HIRONOBU, KONOVALOVA, NINA PETROVNA, LUGOVSKAYA, NATALIYA YURIEVNA
Format Patent
LanguageEnglish
French
German
Published 13.02.2008
Edition7
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:An ameliorating agent for cancer chemotherapy is disclosed, which comprises a chromanol glucoside represented by the following general formula (1) (wherein R , R , R , and R , which are identical or different from each other, stand for a hydrogen atom or a lower alkyl group, R stands for a hydrogen atom, a lower alkyl group, or a lower acyl group, X stands for a monosaccharide residue or an oligosaccharide residue optionally having the hydrogen atom of the hydroxyl group in the saccharide residue substituted with a lower alkyl group or a lower acyl group, n is an integer in the range of 0 - 6, and m is an integer in the range of 1 - 6). According to this invention, a novel ameliorating agent for cancer chemotherapy is provided which acts safely and effectively in a small dosage to enhance the carcinostatic action of an anti-cancer agent in cancer chemotherapy and repressing side effects by cancer chemotherapy as well.
Bibliography:Application Number: EP20020707164