INDOLYL-UREA DERIVATIVES OF THIENOPYRIDINES USEFUL AS ANTI-ANGIOGENIC AGENTS

The invention relates to compounds represented by the formula Iand to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R and R are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of fo...

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Bibliographic Details
Main Authors HE, MINGYING, ZHOU, RU, ROMINES, WILLIAM, III, KANIA, ROBERT, S, CRIPPS, STEPHAN, J, LOU, JIHONG
Format Patent
LanguageEnglish
French
German
Published 08.12.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to compounds represented by the formula Iand to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R and R are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.
Bibliography:Application Number: EP20030702952