THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME AND METHODS OF USE

• Main Authors: ZERHUSEN, BRYAN, D, MACDOUGALL, JOHN, R, ZHONG, MEI, PENA, CAROL, E., A, RASTELLI, LUCA, SPYTEK, KIMBERLY, A, FURTAK, KATARZYNA, ZHONG, HAIHONG, SMITHSON, GLENNDA, GERLACH, VALERIE, LIU, XIAOHONG, VERNET, CORINE, A., M, SHENOY, SURESH, G, VOSS, EDWARD, Z, CASMAN, STACIE, J, ANDERSON, DAVID, W, LI, LI, MILLER, CHARLES, E, BOLDOG, FERENC, L, MEZES, PETER, S
• Format: Patent
• Language: English; French; German
• Published: 06.09.2006
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.