PDE IV inhibitors for treating multiple sclerosis

The present invention is a method of preventing or ameliorating the episodic recurrence of MS, comprising administering an effective amount of selective phosphodiesterase inhibitors of Type IV, e.g., Rolipram, e.g., wherein the severity of the episodic recurrences is ameliorated or the time period b...

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Bibliographic Details
Main Authors HEDGPETH, JOEL, LOESCHMANN, PETER-ANDREAS, GRAF, HERMANN, WACHTEL, HELMUT, SCHMIECHEN, RALPH, PEREZ, DANIEL H
Format Patent
LanguageEnglish
French
German
Published 14.01.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is a method of preventing or ameliorating the episodic recurrence of MS, comprising administering an effective amount of selective phosphodiesterase inhibitors of Type IV, e.g., Rolipram, e.g., wherein the severity of the episodic recurrences is ameliorated or the time period between episodes is lenghtened. The present invention also relates to a pharmaceutical composition for treating MS comprising an effective amount of a combination of a PDE IV inhibitor and an anti-inflammatory or immunomodulatory drug in a pharmaceutically acceptable carrier.
Bibliography:Application Number: EP20030090246