NUCLEIC ACID CONSTRUCTS EXPRESSING VEGF AND HGF, CELLS TRANSFORMED THEREWITH AND THEIR USE FOR INDUCING LIVER REGENERATION AND ALLEVIATION OF PORTAL HYPERTENSION

• Main Authors: GLUZMAN, ZOYA, OTT, MICHAEL, PREIS, MEIR, KOREN, BELLY, TSABA, ADILI, FLUGELMAN, MOSHE, Y, COHEN, TZAFRA
• Format: Patent
• Language: English; French; German
• Published: 11.08.2010
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ENZYMOLOGY; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; PROSTHESES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TREATMENT OR PROTECTION OF EYES OR EARS; VINEGAR; WINE

A method of inducing liver regeneration in a damaged liver tissue region of an individual is provided. The method including the step of providing at least two distinct growth factors to the damaged liver tissue region of the individual, at least one of the at least two distinct growth factors being an angiogenic factor.