SUBTILISIN PROTEASE VARIANTS HAVING AMINO ACID DELETIONS AND SUBSTITUTIONS IN DEFINED EPITOPE REGIONS

The present invention relates to variants of subtilisin-like proteases having decreased immunogenicity relative to their corresponding wild-type proteases. The present invention further relates to such variants additionally having one or more amino acid substitutions in one or more epitope regions o...

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Bibliographic Details
Main Authors SIKORSKI, ELIZABETH, ELLEN, RUBINGH, DONN, NELTON
Format Patent
LanguageEnglish
French
German
Published 22.05.2002
Edition7
Subjects
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Summary:The present invention relates to variants of subtilisin-like proteases having decreased immunogenicity relative to their corresponding wild-type proteases. The present invention further relates to such variants additionally having one or more amino acid substitutions in one or more epitope regions or additionally having one or more stabilizing substitutions. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants.
Bibliography:Application Number: EP20000945315