SUBTILISIN PROTEASE VARIANTS HAVING AMINO ACID DELETIONS AND SUBSTITUTIONS IN DEFINED EPITOPE REGIONS
The present invention relates to variants of subtilisin-like proteases having decreased immunogenicity relative to their corresponding wild-type proteases. The present invention further relates to such variants additionally having one or more amino acid substitutions in one or more epitope regions o...
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Main Authors | , |
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Format | Patent |
Language | English French German |
Published |
22.05.2002
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to variants of subtilisin-like proteases having decreased immunogenicity relative to their corresponding wild-type proteases. The present invention further relates to such variants additionally having one or more amino acid substitutions in one or more epitope regions or additionally having one or more stabilizing substitutions. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants. |
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Bibliography: | Application Number: EP20000945315 |