Nuclease
A strand-specific polynucleotide nickase comprising an endonuclease which comprises a first subunit and a second subunit and which recognises an asymmetric nucleotide recognition sequence, wherein the first subunit comprises a catalytic domain capable of cleaving one strand of a DNA duplex, and the...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
30.01.2002
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | A strand-specific polynucleotide nickase comprising an endonuclease which comprises a first subunit and a second subunit and which recognises an asymmetric nucleotide recognition sequence, wherein the first subunit comprises a catalytic domain capable of cleaving one strand of a DNA duplex, and the second subunit is incapable of cleaving the other strand of the DNA duplex. |
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Bibliography: | Application Number: EP20010304891 |