METHODS FOR THE IDENTIFICATION AND VALIDATION OF FUNCTIONAL INTRACELLULAR TARGETS WITH INTRAMERS OR IN VIVO SELECTION

Described are methods for the identification and validation of (1) functional intracellular targets and (2) nucleic acids (intramers) which are capable of binding to and modifying the function of said intracellular targets. These nucleic acids or, alternatively, compounds showing the same or a simil...

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Bibliographic Details
Main Authors KOLANUS, WALDEMAR, FAMULOK, MICHAEL, BLIND, MICHAEL
Format Patent
LanguageEnglish
French
German
Published 02.01.2002
Edition7
Subjects
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Summary:Described are methods for the identification and validation of (1) functional intracellular targets and (2) nucleic acids (intramers) which are capable of binding to and modifying the function of said intracellular targets. These nucleic acids or, alternatively, compounds showing the same or a similar target specificity and/or effect are useful for the preparation of therapeutics, particularly for gene therapy.
Bibliography:Application Number: EP20000914168