LTA4 HYDROLASE INHIBITORS

The invention relates to compounds which constitute a class of medicaments which have an anti-inflammatory activity and which act by inhibiting leukotriene A4 (LTA4), and enzyme which is responsible for the biosynthesis of leukotriene LTB4, a major proinflammatory mediator. The invention also relate...

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Bibliographic Details
Main Authors DANVY, DENIS, LECOMTE, JEANNE-MARIE, DUHAMEL, LUCETTE, MONTEIL, THIERRY, GROS, CLAUDE, PIETTRE, SERGE, SCHWARTZ, JEANARLES, PLAQUEVENT, JEANRISTOPHE, DUHAMEL, PIERRE, NOEL, NADINE, CHAMARD, OLIVIER
Format Patent
LanguageEnglish
French
German
Published 02.01.2002
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to compounds which constitute a class of medicaments which have an anti-inflammatory activity and which act by inhibiting leukotriene A4 (LTA4), and enzyme which is responsible for the biosynthesis of leukotriene LTB4, a major proinflammatory mediator. The invention also relates to therapeutic anti-inflammatory, applications of these compounds as well as for methods of preparing these compounds.
Bibliography:Application Number: EP20000917145