STEM CELLS BEARING AN FGF RECEPTOR ON THE CELL SURFACE

A composition of substantially purified pluripotent stem cells are positive both for fibroblast growth factor receptor (FGFR) and a phenotype indicative of a primitive state, such as CD34<+>, CD34<->lin<->, Thy-1<+>, AC133<+> or c-kit<+>. The state of being an emb...

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Bibliographic Details
Main Authors WILSON, E., LYNETTE, BURGER, PATRICIA E
Format Patent
LanguageEnglish
French
German
Published 25.07.2001
Edition7
Subjects
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Summary:A composition of substantially purified pluripotent stem cells are positive both for fibroblast growth factor receptor (FGFR) and a phenotype indicative of a primitive state, such as CD34<+>, CD34<->lin<->, Thy-1<+>, AC133<+> or c-kit<+>. The state of being an embryonic stem cell is also a phenotype indicative of a primitive state. This population may be further defined by the subpopulations thereof which have another marker thereon indicative of endothelial cells, such a TIE-1<+>, TEK<+>, CD31<+>, VE-Cadherin<+> or VEGFR<+> or indicative of stromal cells, such as STRO-1<+>.
Bibliography:Application Number: EP19990943982