PROCESSES TO GENERATE SUBMICRON PARTICLES OF WATER-INSOLUBLE COMPOUNDS
Submicron particles of water-insoluble compounds, particularly drugs, are prepared by simultaneously stabilizing microparticulate suspensions of same with surface modifier molecules by rapid expansion into an aqueous medium from a compressed solution of the compound and surface modifiers in a liquef...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French German |
Published |
11.04.2001
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Submicron particles of water-insoluble compounds, particularly drugs, are prepared by simultaneously stabilizing microparticulate suspensions of same with surface modifier molecules by rapid expansion into an aqueous medium from a compressed solution of the compound and surface modifiers in a liquefied gas and optionally homogenizing the aqueous suspension thus formed with a high pressure homogenizer. |
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Bibliography: | Application Number: EP19990930387 |