UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF NEUROGENIC INFLAMMATION

The derivatives of aryl(or heteroaryl)azolylcarbinol (I), in which R1 is an atom of hydrogen or a lower alkyl group; R2 is a dialkylaminoalkyl or azaheterocyclylalkyl radical; Ar is a phenyl or thienyl radical, optionally substituted; and Het is a heterocyclic five-membered azotic aromatic ring that...

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Main Authors FRIGOLA-CONSTANSA, JORDI, MERCE-VIDAL, RAMON
Format Patent
LanguageEnglish
French
German
Published 16.04.2003
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The derivatives of aryl(or heteroaryl)azolylcarbinol (I), in which R1 is an atom of hydrogen or a lower alkyl group; R2 is a dialkylaminoalkyl or azaheterocyclylalkyl radical; Ar is a phenyl or thienyl radical, optionally substituted; and Het is a heterocyclic five-membered azotic aromatic ring that contains from one to three nitrogen atoms, optionally substituted, are suitable for the treatment of neurogenic inflammation, present in different processes, such as diabetes, asthma, cystitis, gingivitis, migraine, dermatitis, rhinitis, psoriasis, inflammation of sciatic and lumbar nerves, gastrointestinal processes, ocular inflammation, etc., in mammals, including man.
Bibliography:Application Number: EP19990919290