PROCESS FOR THE PREPARATION OF A 3(2H)-PYRIDAZINONE- 4-SUBSTITUTED AMINO- 5-CHLORO- DERIVATIVE

The invention relates to novel processes for the preparation of 5-chloro-4-{3-[N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamino]-propylamino-3(2H) pyridazinone of formula (I) and the pharmaceutically acceptable acid addition salts thereof. An important feature of the invention is using 3,4,5-trichlor...

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Bibliographic Details
Main Authors SZTRUHAR, ILONA, RATKAI, ZOLTAN, SIMIG, GYULA, BALAZS, LASZLO, KARANCSI, TAMAS, KOTAY NAGY, PETER, GREFF, ZOLTAN, DOMAN, IMRE, BARKOCZY, JOZSEF, SERES, PETER
Format Patent
LanguageEnglish
French
German
Published 14.09.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to novel processes for the preparation of 5-chloro-4-{3-[N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamino]-propylamino-3(2H) pyridazinone of formula (I) and the pharmaceutically acceptable acid addition salts thereof. An important feature of the invention is using 3,4,5-trichloropyridazone as starting substance of the synthesis.
Bibliography:Application Number: EP19980925869